Children's Hospital Colorado
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Articles

How Precision Medicine Helped Detect a Rare Form of Epilepsy

Scott Demarest, MD, used genetic testing to uncover a rare disorder causing near-constant seizures in two young sisters, showing how precision medicine opens new doors to discovery and treatment.

Articles

Sickle Cell Disease: Exploring Gene Therapy with Casgevy and Lyfgenia

Traditional treatments for sickle cell disease require a strong bone marrow match and carry a risk of rejection and disease. Now, two new therapies revolutionize care by allowing for autologous transplant.

Articles

Bridging Diagnostic Gaps in Pulmonary Fibrosis

An international landmark study developed computed tomography (CT) imaging criteria for diagnosing pulmonary fibrosis specifically in children.

Articles

The Role of PRMT5 in Pediatric High-Grade Gliomas

This study is the first to establish that the gene PRMT5 may play a key role in halting the development of pediatric high-grade gliomas. Learn more about PRMT5 as a promising preclinical drug target.

Articles

Providing ETI for Pregnant Carriers of Babies with Cystic Fibrosis

Some women carrying fetuses with cystic fibrosis (CF) are using Trikafta to prevent complications. Early results are promising, but more research is needed on safety and efficacy.

Articles

Research Advancements in Preventing Parenteral Nutrition-Associated Cholestasis

Our experts identified a potential therapeutic approach that could one day treat or prevent a serious liver disease in young children with intestinal failure caused by prolonged parenteral nutrition.

Articles

Precision Medicine Fellow Brings Genetics to Pediatric Nephrology

As the precision medicine fellow at Children’s Hospital Colorado, Dr. Sarah Nelson-Taylor is advancing genetic understanding in nephrology for pediatric patients with rare, inherited kidney diseases.

Articles

Improving Outcomes for Celiac Disease Through Mass Screening

An effort to mass screen Colorado children for celiac disease resulted in improved health outcomes for patients who were ultimately diagnosed and treated with a gluten-free diet for one year.

Articles

A New Nonhormonal Approach to Endometriosis Pain Treatment

A new multi-institutional trial for the nonhormonal drug cabergoline aims to help reduce pain in adolescents with endometriosis, an important step toward health equity for teens who menstruate.

Articles

Special Care Clinic Dwarfism Research

The Special Care Clinic at Children’s Colorado combines multidisciplinary care with genetic expertise to further research on rare bone diseases like osteogenesis imperfecta and skeletal dysplasia.