Children's Hospital Colorado
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Articles

Cord Blood Lipid Levels Linked to Birth Weight, Doppler Velocimetry of Fetal Vessels in Fetal Growth Restriction Pregnancies

In this study, researchers explored the link between fetal growth restriction and cord blood lipid levels, finding that growth-restricted infants have altered cord blood lipid profiles, with abnormal Doppler flow in fetal vessels. This suggests an influence on intrauterine lipid metabolism.

Articles

Improving Outcomes of Fetal Whole-exome Sequencing With a Multidisciplinary Approach

The Colorado Fetal Care Center established a multidisciplinary Fetal Precision Medicine Board to enhance the efficiency and accuracy of prenatal whole-exome sequencing, effectively addressing challenges such as cost, lengthy turnaround time, and expertise requirements.

Articles

Accelerating the Discovery of Inborn Errors of Immunity

The immunology team at Children’s Hospital Colorado has built a center of excellence to study extremely rare genetic abnormalities that lead to immune diseases, an approach they say can generate knowledge applicable to more common disorders.

Articles

Advanced Genetic Testing to Avert Rare Pregnancy Complications

Through genetic testing, a pregnant woman discovered she carried a rare MAGED2 gene variation linked to Bartter syndrome, potentially threatening both her and her unborn baby's life. Leveraging precision medicine, her doctors at UCHealth and the Colorado Fetal Care Center developed a personalized care plan, successfully carrying her pregnancy to full term and ensuring the health of both mother and baby.

Articles

Improving Options for Pediatric Craniopharyngioma Treatment

The Children's Hospital Colorado Neuroscience Institute is making advances in the treatment of craniopharyngioma, a benign but debilitating brain tumor that primarily affects children. Led by Dr. Todd Hankinson, the Institute has formed a consortium dedicated to researching new treatments and is now leading clinical trials exploring novel therapies.

Articles

Study of Celiac Disease in European, U.S. Children Shows Incidence Varies by Region

A four-country study of children at risk for developing celiac disease (CD) found its incidence by age 10 varied by region, even within the U.S. Learn what U.S. state had the highest incidence.

Articles

Hospitalists’ Perceptions of Pediatric Mental Health Boarding

This study reveals hospitalists’ concerns about pediatric mental health boarding, prompting calls for improved telepsychiatry use and increased mental health training.

Articles

Advancing Craniosynostosis Treatment with Artificial Intelligence

Craniofacial surgery experts at Children's Hospital Colorado are using artificial intelligence (AI) to create personalized, data-driven models that improve treatment outcomes for children with craniosynostosis.

Articles

Understanding Heart Failure in Children After Single Ventricle Surgery

Researchers at Children's Hospital Colorado's Heart Institute are working to understand the mechanisms leading to heart failure in children who have undergone single ventricle surgery. They found that failing single ventricle hearts have dysregulated metabolic pathways and impaired mitochondrial function. By understanding the mitochondria's role in heart failure, researchers are exploring therapeutic options targeting mitochondrial function.

Articles

Hip Dysplasia Treatment and Non-Narcotic Pain Management

Orthopedic surgery researchers at Children’s Hospital Colorado are making strides in hip dysplasia treatment with an innovative whole-patient approach, a focus on non-narcotic pain management and best practices for the Pavlik harness.